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385 Results found Showing results 1-15 out of 385
  • Regular

    Signalling in bacterial chemosensory receptor arrays

    Prof. Vaknin Ady The Hebrew University Israel

    Prof. Parkinson John Sandy University of Utah USA

    Area of Research: Life Science - Microbiology | Bacteriology
    Keywords: Bacterial chemotaxis; sensory receptors; Receptor clustering; Sensory transduction
    2023 | 2023346 | $300000
    Lay Abstract
  • Regular

    Massively parallel functional characterization of gene regulatory elements shaping archaic human evolution

    Dr. Gokhman David Weizmann Institute of Science Israel

    Prof. Ahituv Nadav The Regents of the University of California USA

    Area of Research: Life Science - Genetics, Bioinformatics and Computational Biology | Comparative Genomics & Proteomics
    Keywords: Evolution, functional genomics, gene expression, Neanderthals, Denisovans
    2023 | 2023344 | $300000
    Lay Abstract
  • Regular

    Predicting Structural Assembly Patterns in Adhesion Proteins

    Dr. Rubinstein Rotem Tel Aviv University Israel

    Dr. Wu Yinghao Albert Einstein College of Medicine USA

    Area of Research: Life Sciences | Life Science - Biochemistry
    Keywords: adhesion proteins, protein-protein interactions, membrane proteins
    2023 | 2023336 | $258000
    Lay Abstract
  • Regular

    Mechanism of non-canonical inflammasome activation in macrophages by the endogenous lipid sulfatide

    Prof. Zor Tsaffrir Tel Aviv University Israel

    Dr. Fraser Iain NIH USA

    Area of Research: Life Science - Cell and Developmental Biology | Signal Transduction
    Keywords: Caspase-11; Sulfatide; Inflammasome; LPS; Caspase-4; Inflammation; Non-canonical inflammasome; Caspase-11/4, Sphingolipids; Macrophages
    2023 | 2023335 | $210000
    Lay Abstract
  • Regular

    Unraveling the biosynthetic and regulatory landscape of hydrolyzable tannins and flavonoids at the nexus of the shikimate pathway

    Dr. Tian Li The Regents of the University of California USA

    Prof. Amir Rachel Migal Galilee Research Institute & Tel-Hai College Israel

    Area of Research: Life Science - Plant Sciences | Biochemistry & Metabolism
    Keywords: hydrolyzable tannin, flavonoid, anthocyanin, shikimate, biosynthesis, regulation, transcription factor, pomegranate
    2023 | 2023332 | $300000
    Lay Abstract
  • Regular

    Functional diversification of paralogous genes of the trehalose metabolism pathway in Daphnia response to diverse environmental stresses

    Prof. Ben-Ami Frida Tel Aviv University Israel

    Prof. Yampolsky Lev East Tennessee State University USA

    Area of Research: Life Science - Ecology | Functional ecology
    Keywords: desiccation tolerance, embryonic diapause development, heat tolerance, resting eggs, salinity tolerance, trehalose
    2023 | 2023329 | $198000
    Lay Abstract
  • Regular

    Targeting Nucleolin for Neural Repair in Stroke

    Prof. Fainzilber Michael Weizmann Institute of Science Israel

    Dr. Rishal Ida Weizmann Institute of Science Israel

    Prof. Carmichael S Thomas University of California, Los Angeles USA

    Area of Research: Life Science - Neurobiology | Brain organs & Pathways
    Keywords: Nucleolin, Stroke, Axonal Transport, RNA Localization, Local Translation, Axon Growth, Sprouting
    2023 | 2023327 | $300000
    Lay Abstract
  • Regular

    Oxytocin and Human-Dog Affiliative Interactions

    Prof. Israel Salomon The Hebrew University Israel

    Prof. Kahila Bar-Gal Gila The Hebrew University Israel

    Prof. MacLean Evan University of Arizona USA

    Prof. Zamansky Anna The University of Haifa Israel

    Area of Research: Life Science - Animal Sciences | Behavior, Adaptation and Evolution
    Keywords: oxytocin, genomics, human-dog interaction, canine, social behavior, early environment
    2023 | 2023325
    Lay Abstract
  • Regular

    Cerebellar regulation of coordinated cortical activity in the motor system of the face

    Prof. Prut Yifat The Hebrew University Israel

    Prof. Freiwald Winrich Rockefeller University USA

    Area of Research: Life Science - Neurobiology | Circuits, Neuronal Populations
    Keywords: Facial expressions, cerebellum, motor cortex, motor control
    2023 | 2023321 | $264000
    Lay Abstract
  • Regular

    Identifying the mechanisms underlying persistence potential and drug-induced cellular memory in lung cancer

    Dr. Oren Yaara Tel Aviv University Israel

    Dr. Getz Gad The Broad Institute, Inc. USA

    Area of Research: Medicine - Cancer | Oncology
    Keywords: Persisters, systems biology, cancer
    2023 | 2023320 | $300000
    Lay Abstract
  • Regular

    Delineating the effects of locomotion and postural control challenges on cognitive-motor-autonomic interactions: a virtual reality study

    Prof. Plotnik Meir Medical Research Fund - Sheba Medical Center Israel

    Prof. Wright W. Geoffrey Temple University USA

    Area of Research: Life Science - Neurobiology | Neurophysiology
    Keywords: Postural control, Locomotion, Cognition, Cognitive-motor interactions, Manual control, Affect, Autonomic Nervous System, Virtual reality, Dual-task
    2023 | 2023319 | $300000
    Lay Abstract
  • Regular

    Prospective longitudinal study of 22q11.2 deletion syndrome: integration of exposome and psychosis trajectories

    Prof. Gothelf Doron Medical Research Fund - Sheba Medical Center Israel

    Dr. Taler Michal Medical Research Fund - Sheba Medical Center Israel

    Prof. Gur Raquel University of Pennsylvania USA

    Prof. Sullivan Kathleen Children`s Hospital of Philadelphia USA

    Prof. McDonald-McGinn Donna Children`s Hospital of Philadelphia USA

    Area of Research: Psychobiology | Brain and Behavior
    Keywords: 22q11.2 deletion syndrome, Psychosis, Exposome, Cognition, Inflammation, Oxidative Stress, Metabolomics, Medical Burden
    2023 | 2023318
    Lay Abstract
  • Regular

    Identifying regulatory genes that mediate immunosuppressive signals in macrophages using spatial Perturb-seq

    Dr. Parnas Oren The Hebrew University Israel

    Dr. Hwang William Massachusetts General Hospital USA

    Area of Research: Life Science - Immunology | Tumor Immunology
    Keywords: Pancreatic cancer, spatial transcriptomic,CRISPR screens, macrophages, HMPCITE-seq, Perturb-seq
    2023 | 2023314 | $300000
    Lay Abstract
  • Regular

    Deciphering GPX8-Mediated Lipid Remodeling: Implications for EMT and Ferroptosis Sensitivity

    Dr. Shaul Yoav The Hebrew University Israel

    Dr. Kim Dohoon University of Massachusetts; Medicine USA

    Area of Research: Life Science - Biochemistry | Metabolism
    Keywords: Ferroptosis, GPX8, EMT, lipid remodeling
    2023 | 2023313 | $270000
    Lay Abstract
  • Startup

    Data-driven spatiotemporal characterization of cell death

    Dr. Zaritsky Assaf Ben Gurion University Israel

    Prof. Overholtzer Michael Sloan Kettering Institute for Cancer Res USA

    Area of Research: Life Science - Cell and Developmental Biology | Cell Death
    Keywords: cell death, ferroptosis, quantitative live cell imaging, machine learning, collective cell behavior
    2023 | 2023297 | $75000
    Lay Abstract