Search a Grant

Search again
385 Results found Showing results 31-45 out of 385
  • Regular

    Identification of COX-2 cleavage products and determination of their possible involvement in colon cancer tumorigenesis

    Prof. Barki-Harrington Liza The University of Haifa Israel

    Prof. Chen Xian The University of North Carolina at Chapel Hill USA

    Area of Research: Life Sciences | Life Science - Biochemistry
    Keywords: Cyclooxygenase-2, proteolysis, mass spectrometry, proliferation, inflammation, Catalytic inactivation, Protein interactions, localization
    2023 | 2023247 | $300000
    Lay Abstract
  • Regular

    Mechanistic elucidation of novel CARD11 variants

    Dr. David Liron Ben Gurion University Israel

    Dr. Snow Andrew Uniformed Services U Health Sciences USA

    Area of Research: Life Science - Immunology | Immunogenetics
    Keywords: CARD11, CBM complex, cryo-EM microscopy,lymphoma, CADINS Disease, BENTA disease
    2023 | 2023245 | $278000
    Lay Abstract
  • Regular

    Targeting chromosome 8q gain as a novel therapeutic vulnerability in cancer

    Dr. Ben-David Uri Tel Aviv University Israel

    Prof. Sheltzer Jason Yale University USA

    Area of Research: Medicine - Cancer | Genetics
    Keywords: cancer genetics; genomic instability; aneuploidy; chromosomal instability
    2023 | 2023236 | $300000
    Lay Abstract
  • Regular

    Deciphering the interplay between promoter structure and splicing decisions

    Dr. Mikl Martin The University of Haifa Israel

    Prof. Fiszbein Ana Boston University USA

    Area of Research: Life Science - Molecular Biology and Genomic Research | Genomic Research
    Keywords: gene expression, transcription, splicing, MPRA, genetic variation, functional genomics
    2023 | 2023233 | $300000
    Lay Abstract
  • Regular

    Principles of functional coordination between stromal and immune cells at tissue homeostasis and inflammation

    Dr. Adler Miri The Hebrew University Israel

    Dr. Zhou Xu Boston Children`s Hospital USA

    Area of Research: Life Science - Genetics, Bioinformatics and Computational Biology | Networks & System Biology
    Keywords: Single-cell analysis, Macrophages, Fibroblasts, Division of labor, Systems biology, Cell-cell communication, Inflammation
    2023 | 2023231 | $193500
    Lay Abstract
  • Regular

    Molecular Dissection of Early Changes in Osteosarcomagenesis

    Prof. Aqeilan Rami The Hebrew University Israel

    Prof. Stein Gary University of Vermont; Medicine USA

    Prof. Stein Janet University of Vermont; Medicine USA

    Area of Research: Medicine - Cancer | Oncology
    Keywords: Osteosarcoma, WWOX, p53, mouse models
    2023 | 2023230 | $252000
    Lay Abstract
  • Regular

    Discovery of cancer metabolic vulnerabilities through interrogation of spatiotemporal multiomics

    Prof. Amit Ido Weizmann Institute of Science Israel

    Prof. Wagner Allon University of California USA

    Dr. Jaitin Diego Weizmann Institute of Science Israel

    Area of Research: Life Science - Immunology | Tumor Immunology
    Keywords: Single-cell genomics; Metabolic modeling; Immunometabolism; Tumor immunology; Metabolomics; Spatial transcriptomics; Computational biology; Single cell multi-omics;
    2023 | 2023229 | $300000
    Lay Abstract
  • Regular

    Parasitoid wasps` use of viruses to suppress host immunity

    Dr. Zchori-Fein Einat Agricultural Research Organization Israel

    Dr. Chiel Elad The University of Haifa Israel

    Dr. Schlenke Todd University of Arizona USA

    Area of Research: Life Sciences | Life Science - Immunology
    Keywords: AnvRV virus, Insect symbionts, Anagyrus vladimiri, mealybugs
    2023 | 2023219 | $225000
    Lay Abstract
  • Regular

    Subcellular localization of translation for the hypertrophic growth response

    Prof. Kehat Izhak Technion - Israel Institute of Technology Israel

    Prof. Prosser Benjamin University of Pennsylvania USA

    Area of Research: Medicine | Medicine - Cardiology, Blood and Respiratory Systems (inc.Environmental Factors)
    Keywords: Cardiac hypertrophy, microtubules, localized protein translation
    2023 | 2023218 | $300000
    Lay Abstract
  • Regular

    Developmental roles and mechanisms of mRNA turnover for shaping spatio-temporal gene expression patterns in embryos

    Prof. Rabani Michal The Hebrew University Israel

    Dr. Farrell Jeffrey Allen National Inst of Child Hlth & Human Develop, NIH USA

    Area of Research: Life Sciences | Life Science - Molecular Biology and Genomic Research
    Keywords: embryogenesis, RNA degradation, zebrafish, differentiation, cell specification, metabolic labeling, single-cell RNA-Seq, developmental biology
    2023 | 2023216 | $282000
    Lay Abstract
  • Regular

    Delineating the pathophysiological pathways of corticospinal neurodegeneration

    Prof. Elazar Zvulun Weizmann Institute of Science Israel

    Dr. Fagiolini Michela Boston Children`s Hospital USA

    Dr. Fraiberg Milana Weizmann Institute of Science Israel

    Area of Research: Life Science - Cell and Developmental Biology | Membrane Trafficking
    Keywords: Autophagy, neurodegeneration, HSP, TECPR2, SPG49, HSAN9
    2023 | 2023211 | $300000
    Lay Abstract
  • Regular

    In vitro approaches to study and treat human nonobstructive azoospermia

    Prof. Huleihel Mahmoud Ben Gurion University Israel

    Prof. Orwig Kyle Magee-Womens Research Institute and Foundation USA

    Area of Research: Medicine | Medicine - Child and Human Health, Human Development, Fertility
    Keywords: Male infertility; Non-obstructive azoospermia (NOA); induced pluripotent stem cells (IPSCs), Genetic factors contribute NOA. Spermatogenesis. In vitro differentiation of iPSCs. Gene therapy.
    2023 | 2023209 | $300000
    Lay Abstract
  • Regular

    Exploring Inherited Stress in the Gut-Brain-Obesity Nexus

    Prof. Rosenzweig Tovit Ariel University Israel

    Prof. Pinhasov Albert Ariel University Israel

    Prof. Sabunciyan Sarven Johns Hopkins University USA

    Area of Research: Medicine | Medicine - Metabolic and Endocrine Systems
    Keywords: Stress-coping abilities, obesity, glucose intolerance, insulin resistance, gut microbiome.
    2023 | 2023200 | $246000
    Lay Abstract
  • Regular

    Decoding Plastid Dynamics during Cell Division in Malaria Parasites

    Dr. Florentin Anat The Hebrew University Israel

    Dr. Absalon Sabrina Indiana University; Medicine USA

    Area of Research: Life Science - Microbiology | Parasitology
    Keywords: parasitology, malaria, plastid, organelle, cell cycle, Plasmodium
    2023 | 2023198 | $300000
    Lay Abstract
  • Regular

    Stem cell-laden microgel therapy for discogenic low back pain

    Prof. Seliktar Dror Technion - Israel Institute of Technology Israel

    Prof. Sheyn Dima Cedars Sinai Medical Center USA

    Area of Research: Biomedical Engineering | Tissue Engineering, Stem Cells and Biotechnology
    Keywords: hydrogels, tissue engineering, stem cells, biomaterials
    2023 | 2023191 | $210000
    Lay Abstract