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373 Results found Showing results 316-330 out of 373
  • Regular

    Underlying synaptic mechanisms of sensory adaptation of cortical cells in awake mice

    Prof. Lampl Ilan Weizmann Institute of Science Israel

    Prof. Priebe Nicholas University of Texas USA

    Area of Research: Medicine | Medicine - Neurological and Sensory Systems
    Keywords: adaptation, in-vivo intracelllar recordings, excitation and inhibition, short term synaptic plasticity
    2019 | 2019251 | $249600
    Lay Abstract
  • Regular

    Reciprocal effects of alpha-synuclein on synaptic physiology

    Dr. Gitler Daniel Ben Gurion University Israel

    Prof. Roy Subhojit The Regents of the U of California, UC San Diego USA

    Area of Research: Life Science - Neurobiology | Synaptic & Cellular Neurobiology
    Keywords: alpha-synuclein, synapse, presynaptic, neurotransmission, synaptic vesicle, neurophysiology
    2019 | 2019248 | $320000
    Lay Abstract
  • Regular

    The functions of Smad1/5 in the Development and Survival of Midbrain Dopaminergic Neurons

    Dr. Brodski Claude Ben Gurion University Israel

    Prof. Friedel Roland Icahn School of Medicine of Mount Sinai USA

    Area of Research: Life Science - Cell and Developmental Biology | Cell Morphogenesis
    Keywords: Neurogenesis, neural development, dopaminergic neurons, SMADs, midbrain development, brain organoids
    2019 | 2019246 | $288000
    Lay Abstract
  • Regular

    Association between social and genetic networks in a desert equid and the networks responses to environmental perturbation

    Dr. Bar-David Shirli Ben Gurion University Israel

    Prof. Rubenstein Daniel Princeton University USA

    Prof. Templeton Alan Washington University USA

    Prof. Bouskila Amos Ben Gurion University Israel

    Area of Research: Life Science - Animal Sciences | Behavior, Adaptation and Evolution
    Keywords: Equus hemionus, conservation, equids, fission-fusion, social structure, social behavior, population genetics, polyandry, polygyny, social network, genetic network
    2019 | 2019245 | $256000
    Lay Abstract
  • Startup

    Mass Spectrometry Imaging-guided Discovery of Novel Drugs Against MYC-driven Cancers

    Dr. Margulis Katy The Hebrew University Israel

    Prof. Felsher Dean Stanford University; Medicine USA

    Area of Research: Biomedical Engineering | Biological Systems and Signals, Control Systems and Imaging
    Keywords: Mass spectrometry imaging, MYC, lipogenesis, metabolism, conditional transgenic mouse models
    2019 | 2019237 | $75000
    Lay Abstract
  • Regular

    The role of HMGB proteins in the regulation of virulence genes and sexual development in the malaria parasite Plasmodium falciparum

    Prof. Dzikowski Ron The Hebrew University Israel

    Prof. Llinas Manuel Pennsylvania State University USA

    Area of Research: Life Science - Microbiology | Parasitology
    Keywords: malaria, Plasmodium falciparum, gene expression, virulent genes, sexual development
    2019 | 2019236 | $320000
    Lay Abstract
  • Regular

    Exploring the involvement of the actin cytoskeleton and its associated adhesion structures in spindle orientation

    Dr. Luxenburg Chen Tel Aviv University Israel

    Dr. Williams Scott The University of North Carolina at Chapel Hill USA

    Area of Research: Life Science - Cell and Developmental Biology | Cell Differentiation
    Keywords: spindle orientation, asymmetric cell division, actin cytoskeleton, actomyosin, adhesion, integrins, adherens junctions, epidermis, skin, development
    2019 | 2019230 | $307200
    Lay Abstract
  • Regular

    Identifying drivers and vulnerabilities of chromosome 16q loss in Ewing sarcoma

    Dr. Ben-David Uri Tel Aviv University Israel

    Prof. Filbin Mariella Dana-Farber Cancer Institute USA

    Area of Research: Medicine | Medicine - Cancer
    Keywords: Cancer genetics; aneuploidy; Ewing sarcoma
    2019 | 2019228 | $448000
    Lay Abstract
  • Startup

    Mesoscale dynamics of different cortical layers during spontaneous and engaged behavior

    Dr. Gilad Ariel The Hebrew University Israel

    Prof. Reimers Mark Michigan State University USA

    Area of Research: Medicine - Neurological and Sensory Systems | Clinical Neurobiology
    Keywords: Mesoscale; Wide-field imaging; Layer 2/3; Layer 5; Short-term memory; cortical dynamics; Sensory integration; Laminar profile; Optogenetics; Microscale
    2019 | 2019223 | $74048
    Lay Abstract
    Final Summary
  • Regular

    Mobile cognition- novel virtual reality based paradigm to study cognitive – motor interactions in the context of fall risk in ageing

    Dr. Plotnik Meir Medical Research Fund - Sheba Medical Center Israel

    Prof. Wright W. Geoffrey Temple University USA

    Area of Research: Medicine | Medicine - Neurological and Sensory Systems
    Keywords: Virtual reality, Cognition, Gait, Oculomotor, Manual control
    2019 | 2019222 | $320000
    Lay Abstract
  • Regular

    Integrating phylogenomic tools and biodiversity discovery in subterranean habitats of the Levant: population genomics and speciation of troglomorphic arachnids

    Dr. Gavish-Regev Efrat The Hebrew University Israel

    Prof. Sharma Prashant University of Wisconsin-Madison USA

    Area of Research: Life Science - Ecology | Evolutionary ecology, Systematics and Phylogeny
    Keywords: Adaptation, Araneae, Amblypygi, Biogeography, Cave, Genomics, Levant, Opiliones, Phylogeny, Speciation, Systematics, Taxonomy, Troglomorphism
    2019 | 2019216 | $240000
    Lay Abstract
    Final Summary
  • Regular

    ROLE OF MECHANOTRANSDUCTION IN THE IMMUNE SYSTEM: FROM CYTOSKELETAL DYNAMICS TO SIGNALING CASCADES AND IMMUNE RESPONSE

    Prof. Barda-Saad Mira Bar Ilan University Israel

    Prof. Burkhardt Janis Children`s Hospital of Philadelphia USA

    Area of Research: Life Sciences | Life Science - Immunology
    Keywords: TCR signaling, natural killer activation, cytoskeleton, lymphocyte activation
    2019 | 2019211 | $320000
    Lay Abstract
  • Regular

    Role of a novel luxotonic amacrine cell in retinal light adaptation and crossover inhibition

    Dr. Sabbah Shai The Hebrew University Israel

    Prof. Borghuis Bart University of Louisville USA

    Area of Research: Medicine - Neurological and Sensory Systems | Ophthalmology and Eye
    Keywords: Light adaptation, intrinsically photosensitive retinal ganglion cells (ipRGCs), retina, amacrine cells, serial electron microscopy, electrophysiology, neuromodulation, calcium imaging, optogenetics.
    2019 | 2019209 | $262400
    Lay Abstract
  • Regular

    Non-canonical action of Bax at the nuclear envelop

    Prof. Stein Reuven Tel Aviv University Israel

    Prof. Worman Howard Columbia University; Physicians & Surgeons USA

    Area of Research: Life Science - Cell and Developmental Biology | Cell Death
    Keywords: Bax, nucleus, nesprin, LINC complex, nuclear membrane, cell death
    2019 | 2019204 | $281600
    Lay Abstract
  • Regular

    Targeting LXR-Cholesterol Axis In Glioblastoma-Associated Microglia

    Dr. Mayo Lior Tel Aviv University Israel

    Prof. Mischel Paul Stanford University USA

    Area of Research: Medicine - Cancer | Cell and Gene Therapy
    Keywords: LXR, Cholesterol, Microglia, Glioblastoma
    2019 | 2019197 | $253200
    Lay Abstract